What is the primary purpose of a buffer solution in IV preparation?

The primary purpose of a buffer solution in IV preparation is to neutralize pH and prevent patient discomfort. Maintaining the pH within a narrow range is crucial in intravenous solutions to ensure compatibility with blood and bodily fluids. An unbuffered solution can lead to significant fluctuations in pH during storage, preparation, or after administration, which may cause irritation or discomfort to the patient’s veins and tissues. A buffer helps stabilize the pH, ensuring that the IV fluid is safe, effective, and less likely to cause adverse reactions when infused.

In the context of IV therapy, the discomfort experienced by patients can arise if the solution is too acidic or too alkaline. Therefore, using a buffer allows healthcare providers to prepare solutions that are physiologically appropriate and more comfortable for the patient during the infusion process.