What can be a consequence of incompatible additives during compounding?

The consequence of incompatible additives during compounding is the presence of particulate matter in the final solution. When additives do not blend well chemically or physically, they may form precipitates or aggregates, leading to the formation of particles that can be harmful if administered to a patient. These particles can obstruct blood vessels or cause adverse reactions when injected. Therefore, careful evaluation of the compatibility of all substances involved in compounding is critical to ensure patient safety and drug efficacy.

Incompatible additives do not improve nutrient absorption or enhance medication delivery; instead, they can jeopardize the stability and safety of the entire compounded preparation. Additionally, while the goal of compounding may include minimizing microbial contamination, compatibility issues would not contribute to that purpose and could, in fact, introduce new risks to the compounded solution.